Influenced By Him, And Probably Even More

Scientific Research Is One Of The Most Exciting And Rewarding Of Occupations.

In This Atmosphere I Soon Became Interested In Nucleic Acids.

And Indeed This Theme Has Been At The Centre Of All My Research Since 1943, Both Because Of Its Intrinsic Fascination And My Conviction That A Knowledge Of Sequences Could Contribute Much To Our Understanding Of Living Matter.

A Dna Sequence For The Genome Of Bacteriophage Φx174 Of Approximately 5,375 Nucleotides Has Been Determined Using The Rapid And Simple 'plus And Minus' Method. The Sequence Identifies Many Of The Features Responsible For The Production Of The Proteins Of The Nine Known Genes Of The Organism, Including Initiation And Termination Sites For The Proteins And Rnas. Two Pairs Of Genes Are Coded By The Same Region Of Dna Using Different Reading Frames.

Until 1943 I Received No Stipend. I Was Able To Support Myself As My Mother Was The Daughter Of A Relatively Wealthy Cotton Manufacturer.